Second Generation Amphiphilic Poly-Lysine Dendrons Inhibit Glioblastoma Cell Proliferation without Toxicity for Neurons or Astrocytes
Fig 10
Dendron effect on U87 glioblastoma cell mitochondrial transmembrane potential and ROS production.
U87 human glioblastoma cells were exposed to to vehicle (bdH2O; ○) or increasing concentrations of dendrons F4 (●); F6 (□); F11(■) and F15 (▽) for 72 h for the indicated times. Either (A) ROS production or (B) mitochondrial transmembrane potential were measured as indicated in Material and Methods. Data represent mean ± s.e.m. of 28 to 30 cells. **p<0.05; ***p<0.01 when compared to vehicle.