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Effect of Sodium-Glucose Co-Transporter 2 Inhibitor, Dapagliflozin, on Renal Renin-Angiotensin System in an Animal Model of Type 2 Diabetes

Fig 6

Changes in glomerular or tubulointerstitial phenotypes in LETO or OLETF rats.

Representative sections for assessing the inflammatory cell infiltration (immunostaining for ED-1, x 200), glomerular expansion (PAS, x 400) and tubulointerstitial fibrosis (Masson trichrome, x 200) in LETO (LT) and OLETF rats with saline (OL-C), dapagliflozine (OL-DA) or voglibose (OL-VO) treatment.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0165703.g006