Fetal Lymphoid Progenitors Become Restricted to B-1 Fates Coincident with IL-7Rα Expression
Fig 3
FL-CLPs do not efficiently engraft and differentiate in adult bone marrow.
(A) Flow cytometry analyses are shown for bone marrow cells from SCID mice transplanted four weeks earlier with 8-wk-ABM- or FL-CLPs from BALB/cA mice. PreB cells (cμ+ sμ-) are indicated within the B220+ gate. (B) Absolute numbers of cμ+ sμ- preB cells per femur. Each dot represents data form single mouse. The data are pooled from four experiments (n = 14). (**P < 0.01, N.S.: not significant)