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Management of flu-like syndrome with cetirizine in patients with relapsing-remitting multiple sclerosis during therapy with interferon beta: Results of a randomized, cross-over, placebo-controlled pilot study

Fig 2

Change of FLS severity (VAS) from before (0 h) to after interferon-ß injection (4 h) (primary endpoint).

Visual analog (VAS) scores were collected at 4 weeks in each treatment sequence. Data shown are total mean VAS scores. ANCOVA analysis was performed on the ITT population (N = 39).

Fig 2

doi: https://doi.org/10.1371/journal.pone.0165415.g002