Feasibility of In-Vivo Simulation of Acute Hemodynamics in Human Atrial Fibrillation
Fig 1
General principle of the method for simulation of AF.
(A) QRS complexes were identified in an Holter ECG recording of AF to obtain a text string of the corresponding RR intervals. (B) The sequence of RR intervals was loaded to an Arduino-based microcomputer. The microcomputer generated square-wave pulses according to the RR interval sequence. (C) The pulses from the microcomputer were sensed by a cardiac stimulator, which was set to a sense-pace mode. (D) Pacing was performed by catheters in the coronary sinsus (i.e., left atrial pacing) and at the His bundle region. A pigtail cathter was inserted antegradely to measure the LV pressure.