LIM-Only Protein 4 (LMO4) and LIM Domain Binding Protein 1 (LDB1) Promote Growth and Metastasis of Human Head and Neck Cancer (LMO4 and LDB1 in Head and Neck Cancer)
Fig 7
Biological processes highlighted by iPathway Guide from differentially expressed genes in LDB1 knockout compared to wild-type VU-SCC-1729 cells.
Numbers represent percentage of genes in each category differentially expressed in KO vs. wild-type cells using a threshold of 0.05 for statistical significance and 2 for absolute log expression change. P values for the pathways identified were: ECM-receptor interaction (P = 0.0000527), pathways in cancer (P = 0.001), TGF-β signaling (P = 0.002), transcriptional misregulation in cancer (P = 0.002), and PI3K-Akt signaling (P = 0.003).