Metagenomic Analysis of the Sponge Discodermia Reveals the Production of the Cyanobacterial Natural Product Kasumigamide by ‘Entotheonella’
Fig 2
The biosynthetic gene cluster and proposed biosynthetic pathway to kasumigamide.
(a) ORFs encoded in the putative kasumigamide biosynthetic gene cluster, kasA-I. Double-headed arrows show the location of pDCYN1-2. The ORFs related to PKS-NRPS are highlighted in red. Putative transposases are colored in green. (b) The domain organization and proposed biosynthetic pathway to kasumigamide.