Fibronectin Extra Domain A Promotes Liver Sinusoid Repair following Hepatectomy
Fig 4
EIIIA promotes expression of the vasculature marker VE-cadherin following PHx.
Frozen liver sections taken at day 2 after PHx were stained for VE-cadherin (white). Livers from female and male wild type mice showed increased staining for VE-cadherin (A, C) compared to livers from EIIIA-cFN null mice (B, D). Scale bar, 50 μm. (E, F) Quantification = minimum to maximum % VE cadherin positive area measurements with line at mean, EIIIA+/+ (n = 10; 5 female, 5 male); EIIIA-/- (n = 10; 5 female, 5 male). * p<0.05.