Miltefosine Suppresses Hepatic Steatosis by Activating AMPK Signal Pathway
Fig 5
Effects of compound C on lipid metabolism and AMPK signal pathway in the mouse liver.
(A-D) Levels of triglycerides (A, C) and cholesterol (B, D) in the mouse serum and liver were determined. n = 7. (E-F) Liver lipid accumulation was assessed by HE staining (E) and oil red staining (F). (G) Representative western blots of AMPK signal pathway in the mouse liver. n = 5. (H-J) RT-PCR measurements for mRNA levels of CPT1A (H), SREBP1C (I), FAS (J) and GAPDH (K) in the liver. n = 7. Data are expressed as the mean ± SEM. * P < 0.05, ** P < 0.01.