Toward a Differential Diagnosis of Hidden Hearing Loss in Humans
Fig 2
Electrocochleography shows evidence for cochlear synaptopathy in the high-risk group.
A Averaged waveforms (±SEMs) from each group in response to clicks delivered at 9.1 Hz in alternating polarity at 94.5 dB nHL. SP and AP are measured from baseline to peak, as illustrated. B: Increasing click rate from 9.1 Hz to 40.1 Hz decreases AP without affecting SP: mean waveforms from 6 subjects are shown. C: Mean SP/AP ratio is nearly twice as high in the high-risk vs. the low-risk group. This difference remains when subjects are separated by sex. D: The difference in SP/AP ratios arises from both an increase in the SP and a decrease in the mean AP, although only the SP differences are statistically significant. All data are means (±SEM). ***p<0.001; **p<0.01.