An Amphotericin B Derivative Equally Potent to Amphotericin B and with Increased Safety
Fig 11
Comparative action of Amphotericin B and derivative A21 on Candida albicans ATCC 10231 (A), Candida albicans ATCC 752 (B) and Candida krusei ATCC 6258 (C).
Cells were incubated for 24 h at 37 C under aerobic conditions, stained with propidium iodide (PI). Antifungal activity was determined by flow cytometry. The results are presented as means ± SD of 3 independent experiments. *p < 0.05 is the comparison with control value. #p< 0.05 the comparison with AmB.