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Plasma Level of Placenta-Derived Macrophage-Stimulating Protein -Chain in Preeclampsia before 20 Weeks of Pregnancy

Fig 7

Immunohistochemical analysis of the placentas revealed that the patients with PE exhibited significantly increased plasma MSP staining (IOD [SUM] = 8862.37±2064.42) compared with the healthy pregnant controls (IOD [SUM] = 447.92±114.72, P <0.001).

A significant difference in MSP staining was observed between the PE group without severe features (IOD [SUM]: 12192.65±5325.56) and the PE group with severe features (4104.83±2383.06; P = 0.021).

Fig 7

doi: https://doi.org/10.1371/journal.pone.0161626.g007