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Protective Effect of ALA in Crushed Optic Nerve Cat Retinal Ganglion Cells Using a New Marker RBPMS

Fig 5

RBPMS expressing alpha cells and their density distribution pattern.

A-C illustrate micrographs of RBPMS-alpha RGCs photographed at 1, 5, and 10mm from the AC. Scale bar: 20μm. Arrows depict alpha cells. D shows density distribution pattern of RBPMS-alpha RGCs from a normal cat retina. Each number represents the total number of alpha cells encountered within the sampling field. The size of sampling area was 1×1 mm2. The distance between centers of two neighboring sampling fields was 1 mm. The peak density at the AC was 186/mm2. The dashed circle in the center depicts the optic disk. The edge of the visual streak is defined as local alpha cell density greater than 20/mm2. The area encircled by the solid line represents the visual streak. Scale bar: 5 mm.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0160309.g005