Multi-Layer Mechanical Model of Glagov Remodeling in Coronary Arteries: Differences between In-Vivo and Ex-Vivo Measurements
Fig 6
Remodeling of ex-vivo and in-vivo vessels.
(a) and (b): Time evolution of ex-vivo and in-vivo vessels as they undergo identical uniform growth in the intima. The ex-vivo vessel is unpressurized with P = 0 while the in-vivo vessel is subject to a luminal blood pressure of P = 110 mmHg. (c) and (d) are the respective plots of lumen area vs. plaque area which are qualitatively different. Glagov’s ex-vivo data suggested that during the early stages of atherosclerosis, the lumen area increased by 2.3 mm2 for every mm2 growth of plaque (dashed line in (c)).