microRNA-153 Targets mTORC2 Component Rictor to Inhibit Glioma Cells
Fig 3
miR-153 overexpression inhibits glioma cell growth, and activates cell apoptosis.
Exact same number of stable glioma cells (U87MG or U373MG lines) expressing miR-153, microRNA-control (“miR-C”) or empty vector (“pSuper-puro”) were subjected to MTT assay (A and B) or clonogenicity assay (C and D) to analyze of cell growth; Apoptosis level in these cells was also tested by Histone DNA ELISA assay (E and F). Bars stand for mean ± SD. * p < 0.05 vs. “miR-C” group (n = 6).