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Frontal Lobe Contusion in Mice Chronically Impairs Prefrontal-Dependent Behavior

Fig 1

Frontal Lobe CCI results in a cavitation at site of injury.

A. 40 days post-injury, qualitative NeuN staining reveal normal morphology in sham control animals (top) and a cavitation at site of injury in animals that had received a TBI (bottom). B. Injured animals showed approximately 25% cortical tissue loss (n = 3/group; Student’s t-Test; **p < 0.01).

Fig 1

doi: https://doi.org/10.1371/journal.pone.0151418.g001