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Role of UBIAD1 in Intracellular Cholesterol Metabolism and Vascular Cell Calcification

Fig 3

Effects of cholesterol concentration on matrix calcification and osteoblastic differentiation.

Matrix calcium (A), ALP activity (B) and intracellular cholesterol (C) increased in a dose-dependent manner in HUVSMCs treated with CM with the addition of cell-permeable cholesterol for 72 h. *P < 0.05, #P < 0.01, compared with cholesterol 0 μmol/L.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0149639.g003