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Cervical Cytology Specimen Stability in Surepath Preservative and Analytical Sensitivity for HPV Testing with the cobas and Hybrid Capture 2 Tests

Fig 5

Change in cobas Ct and HC2 ratio over 12 weeks.

Cobas stability for samples with and without pretreatment for the (A) ‘Other HR-HPV’, (B) HPV16, (C) and β-globin control channels, as well as (D) HC2 results are shown. Differences were calculated by subtracting values at baseline from values at each of the time point of the stability study (whiskers are defined by Tukey; boxes show the interquartile range; mean is indicated by +; dots represent outliers). The number of positive sample pools (n) at each time/treatment point is shown.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0149611.g005