Aldosterone Induces Renal Fibrosis and Inflammatory M1-Macrophage Subtype via Mineralocorticoid Receptor in Rats
Fig 7
(A) Representative images showing CD68 staining in control+PBS liposome (Control+Lipo), aldosterone+PBS liposome (Aldo+Lipo), control+clodronate liposome (Control+Clodr), or aldosterone+clodronate liposome (Aldo+Clodr) treated animals. Quantitative analyses of CD68 protein (B) and mRNA (C) levels in treated rats. Quantitative analyses of Arg2 (D) and ED-2 (E) protein levels and IL-10 (F), Arg 1 (G) iNOS (H) and INFγ (I) mRNA expression in treated rats.
Data are expressed as mean ± SEM. *p<0.05 vs Control+Lipo; #p<0.05 vs. Aldo+Lipo.