Cell to Cell Variability of Radiation-Induced Foci: Relation between Observed Damage and Energy Deposition
Fig 8
Density plot of normalized RIF count per nucleus and normalized computed specific energy per volume of 1.6 μm3.
(A), (B) and (C) Density plot of normalized RIF count per nucleus measured after exposure of cells to macroscopic doses of 0.5 (light grey line), 1 (dark grey line) and 2 Gy (black line) for 3 different sources of radiation: 60Co, 4 MVp X-rays and 200 kVp X-ray, respectively. (D) Density plot corresponding to the distribution of normalized computed specific energy per volume of 1.6 μm3. This was calculated from data generated with Eq 3, an assumption of a normal distribution, and the same number of events as in the 60Co biological experiments. The light grey, dark grey and black lines correspond to macroscopic doses of 0.5, 1 and 2 Gy respectively.