Mutational Landscapes of Sequential Prostate Metastases and Matched Patient Derived Xenografts during Enzalutamide Therapy
Fig 3
Validation of gene fusion products identified by RNA seq.
The upper gel images showed the targeted amplification products, and the lower gel images showed the loading control amplification (GAPDH). (A) The amplification products for PNPO-TMPRSS2 fusion was detected in the xenograft sample V1/xeon/C/A. (B) TRIP4-TMPRSS2 fusion was detected in V2/xeno/A/A1. (C) Three different types of TMRPSS2-ETV4 fusions were detected in V2/Xeno/A. The sample V1/Xeno/A1 was used as negative control.