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Non-Invasive Targeted Peripheral Nerve Ablation Using 3D MR Neurography and MRI-Guided High-Intensity Focused Ultrasound (MR-HIFU): Pilot Study in a Swine Model

Fig 7

Light microscopy images of peripheral nerves at 40x magnification, Masson’s trichrome staining.

A Normal appearance of myelin on Masson’s trichrome; myelin sheaths stain purple-red (black arrow). B Section of treated peripheral nerve at the center of the lesion showing absence of purple-red staining (arrow) indicating acute damage to the myelin sheaths. Asterisk (*) indicates subperineural edema.

Fig 7

doi: https://doi.org/10.1371/journal.pone.0144742.g007