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Correlated Evolution of Nucleotide Positions within Splice Sites in Mammals

Fig 4

Dinucleotide frequencies within the region of periodic correlations (positions (-12, -7)) of PPT.

Observed/expected ratio of dinucleotide frequencies within PPT (positions (-12, -7)) and within adjacent intron. Dinucleotides are ordered by the observed/expected ratio within PPT, from low to high. The expected values were obtained based on mononucleotide content. The significance of the difference between observed/expected ratio within PPTs and within adjacent introns are indicated: * 0.01 < p ≤ 0.05; ** 0.001 < p ≤ 0.01; *** p ≤ 0.001; ns p > 0.05.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0144388.g004