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Transient Intervals of Hyper-Gravity Enhance Endothelial Barrier Integrity: Impact of Mechanical and Gravitational Forces Measured Electrically

Fig 1

Experimental set-ups.

A.1) Large Diameter Centrifuge (LDC) with outer gondolas for application of hyper-gravity and the central gondola for rotational controls. A.2) Measurement set-up for quantification of endothelial characteristics in one of the outer gondolas. The set-up consisted of ECIS system, PC and incubator. B) Random Positioning Machine (RPM) for simulation of near weightlessness. C) Pump-system for application of fluid shear stress. D) Custom made pressure vessel for exertion of hydrostatic pressure.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0144269.g001