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MAS C-Terminal Tail Interacting Proteins Identified by Mass Spectrometry- Based Proteomic Approach

Fig 3

Ingenuity Pathway Analysis (IPA) of protein hits.

List of IPA predicted (A and D) top 10 signaling networks, (B and E) top 10 function categories and (C and F) disease categories involving protein hits from (A, B and C) HEK293 and (B, E and F) HL-1 and Human cardiac tissue samples. In panels A, B, D and E a p-value of less than 0.05 (or -log(p-value) < 1.3) is considered statistically significant. In panels C and F, the numbers of protein hits that are involved in a particular disease or functional category are expressed as a percentage of total protein hits that were included in the analysis and shown as a bar graph which is truncated to show categories with greater than 30% representation.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0140872.g003