Gedunin and Azadiradione: Human Pancreatic Alpha-Amylase Inhibiting Limonoids from Neem (Azadirachta indica) as Anti-Diabetic Agents
Fig 7
Ligand binding studies by fluorescence.
Quenching of intrinsic fluorescence. (A) Azadiradione bound HPA. (B) Gedunin bound to HPA. Insets: Determination of dissociation constant (Kd) using one site binding analysis. Linear Van't Hoff plot of azadiradione (C) and gedunin (D) bound to HPA.