Inactivated Eyedrop Influenza Vaccine Adjuvanted with Poly(I:C) Is Safe and Effective for Inducing Protective Systemic and Mucosal Immunity
Fig 7
No detection of contrast medium on the olfactory bulbs from mice administered eyedrops.
Female BALB/c mice were administered 10 μl or 50 μl of contrast medium by eyedrop or IN, respectively. After 30 min of contrast medium treatment, CT pictures of the brains of each mouse were taken. Frontal view (A), top view (B), or dimmed top view (C). Inner dashed circle, olfactory bulbs; blue arrows and red dots, spots of the contrast medium.