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Association of White Blood Cell Count and Differential with the Incidence of Atrial Fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study

Fig 2

Association between total white blood cell count and incident atrial fibrillation presented as hazard ratio (solid line) and 95% confidence intervals (shaded area), Atherosclerosis Risk in Communities Study, 1987 to 2010.

*Cox proportional hazards model using restricted cubic splines with knots at the 5th, 27.5th, 50th, 72.5th and 95th percentiles and adjustment for age, race, and sex. The reference is the median value of the total white blood cell count (hazard ratio = 1), and the histogram represents the frequency distribution of the total white blood cell count in the study sample.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0136219.g002