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Impaired Cell Cycle Regulation in a Natural Equine Model of Asthma

Fig 2

Venn diagrams illustrating the number of DE genes between RAO and control horses.

Panel A illustrates the number of DE genes upon each stimulation across all horses. The panels B-E further differentiate this dependent on the three different cohorts. (B) Unstimulated cells (mock), followed by cells stimulated with (C) recombinant cyathostomin antigen (RCA), (D) lipopolysaccharides (LPS), and (E) hay dust extract (HDE). The numbers represent the number of significantly up (↗) and down (↘) regulated genes in RAO samples compared to control samples.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0136103.g002