Lung Beractant Increases Free Cytosolic Levels of Ca2+ in Human Lung Fibroblasts
Fig 2
The pattern and initial spike-amplitude of the Ca2+ response to beractant depend on resting [Ca2+]i.
A) Resting [Ca2+]i measured in quiescent, non stimulated Fura-2 loaded NHLF that presented the correspondent Ca2+ signal pattern indicated in labels in response to beractant (left). Amplitude of the initial Ca2+ spike evoked by beractant (right). B) Initial spike amplitude/basal [Ca2+]i (ΔR/Ri; ΔR was defined as the difference between the peak [Ca2+]i after stimulation and the value of the resting [Ca2+]i, where Ri is the basal level of R). Results, expressed as means ± SE were analyzed statistically by Student's t test. ** p <0.01, **** p <0.0001.