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A Fine Balance of Dietary Lipids Improves Pathology of a Murine Model of VCP-Associated Multisystem Proteinopathy

Fig 2

Survival curves of WT, VCPR155H/+, and VCPR155H/R155H mice on normal and varying lipid-enriched diets.

Kaplan-Meier survival probability (%) analysis for the WT, VCPR155H/+, and VCPR155H/R155H pregnant dams placed on the (A) 6% normal diet, (B) 9% LED, (C) 12% LED, (D) 30% LED, and (E) 48% LED. (F) Combined survival curve of all the LED regimens for the WT, VCPR155H/+, and VCPR155H/R155H. The number of mice analyzed per experiment is 35–40.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0131995.g002