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Amyloid β Oligomeric Species Present in the Lag Phase of Amyloid Formation

Fig 5

SV analysis of Aβ42 at different initial concentrations.

The noise corrected data (dots) superimposed with fitted curves (lines) from c(s) analysis, and the residuals plot attached below, are shown for 40 μM (A), 80 μM (B), and 160 μM (C) initial concentrations of Aβ42. For clarity, only every second scan and every third data point is shown. The combined c(s) distributions for 40 μM (cyan) measured at 20°C, 80 μM (magenta) measured at 10°C, and 160 μM (blue) measured at 10°C are shown in (D). The monomer peak below 1 S has been excluded from the plot.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0127865.g005