Sex Hormones Promote Opposite Effects on ACE and ACE2 Activity, Hypertrophy and Cardiac Contractility in Spontaneously Hypertensive Rats
Fig 5
Densitometric analysis of Western blots.
(A) SERCA2a; (B) phospholamban (PLB), (C) PLB to SERCA2a ratio, in hearts from male and female sham and gonadectomized rats. (SM: sham male; SF: sham female; GM: gonadectomized male; GF: gonadectomized female). The values are expressed as the means ±S.E.M (n = 6 per group). *P < 0.05 vs. females of the same group; +P < 0.05 vs. sham animals of the same sex (two-way ANOVA and Fischer test).