Articular Joint Lubricants during Osteoarthritis and Rheumatoid Arthritis Display Altered Levels and Molecular Species
Fig 4
Percentage composition of phosphatidycholine (PC) species in human SF.
PC species were quantified by ESI-MS/MS in 16 control SF (shaded bars), 27 eOA SF (hatched bars), 22 lOA SF (open bars), and 20 RA SF (grey bars) samples as described in Methods. Species were assigned based on the assumption that only FAs with an even number of carbon atoms are present. Subsequently, the percentage was calculated, defining total PC as 100%. Data are presented as the median and interquartile ranges. Significance was defined as follows: a: p≤0.05: control vs. RA; b: p≤0.05: control vs. eOA; c: p≤0.05: eOA vs. late OA; d: p≤0.05: eOA vs. RA, e: p≤0.05: eOA vs. RA; and f: p≤0.05: lOA vs RA.