Calpain-Mediated Degradation of Drebrin by Excitotoxicity In vitro and In vivo
Fig 2
Losses of f-actin and drebrin occur concomitantly after NMDA treatment.
(a–h) Immunostaining of rat hippocampal neurons with antibodies against drebrin A/E (C-term), NeuN, and phalloidin (f-actin). (a–d) Control neurons. (e–h) Neurons that were treated with NMDA for 4 h. The arrows indicate NeuN-positive cells (neurons). Scale bar: 10 μm.