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Mapping Molecular Differences and Extracellular Matrix Gene Expression in Segmental Outflow Pathways of the Human Ocular Trabecular Meshwork

Fig 1

Segmental flow in perfused human eyes.

En face image of a whole human eye labeled with Qtracker-655 (red) during perfusion. The perfused tissue was cut into approximately 8 wedges and all were imaged en face by confocal microscopy. En face images were positionally labeled and then photo-merged digitally to create a collage using Adobe Photoshop software. Regions of high and low labeling demonstrate the segmental nature of outflow with labeled brackets indicating examples of each region. Gaps reflect razor blade cut sites. Blue is autofluorescence of the TM tissue.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0122483.g001