Functional Lung MRI in Chronic Obstructive Pulmonary Disease: Comparison of T1 Mapping, Oxygen-Enhanced T1 Mapping and Dynamic Contrast Enhanced Perfusion
Fig 1
Comparison of T1 and perfusion characteristics.
Normal T1 mapping at room air (left), T1 mapping after 100% O2 (middle), and DCE lung perfusion (right) (zonal scores = 0 each) of a 29-year-old healthy proband (A). 59-year-old patient with GOLD stage II showing minor T1 abnormalities at room air (score = 1), normal ΔT1 after 100% O2 (score = 0) and minor perfusion abnormalities (score = 1) of the middle and lower lung zones (area between white arrows), reflecting lung areas with intact ventilation and simultaneous perfusion impairment (B). Severe T1 abnormalities at room air, abnormal ΔT1 after 100% O2 and perfusion abnormalities (score = 2 each) affecting the entire lung of a 75 year old patient with GOLD stage II (C).