Unprecedented Therapeutic Potential with a Combination of A2A/NR2B Receptor Antagonists as Observed in the 6-OHDA Lesioned Rat Model of Parkinson's Disease
Figure 1
Quantification of TH and NeuN in the dopaminergic system after 6-OHDA lesioning.
Intensity of TH and NeuN positive immunostaining of the substantia nigra pars compacta (left) and striatum (right) in rats (n = 24) following administration of 10 µg of 6-OHDA in the medial forebrain bundle of the right hemisphere. Immunostaining was performed in rats having received vehicle treatment only.