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Markers of Bone Metabolism Are Affected by Renal Function and Growth Hormone Therapy in Children with Chronic Kidney Disease

Fig 2

Distribution of serum bone marker concentrations in 510 pediatric CKD patients. Data are expressed as standard deviation scores (SDS).

The shaded area depicts the normal range (5th to 95th percentile of biomarker concentrations in healthy children)[8]. Asterisks indicate significant deviation from distribution in the reference population (*: p<0.05, **: p<0.0001 compared to healthy controls).

Fig 2

doi: https://doi.org/10.1371/journal.pone.0113482.g002