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The Actin Targeting Compound Chondramide Inhibits Breast Cancer Metastasis via Reduction of Cellular Contractility

Figure 5

Chondramide does not influence EGF-R signalling.

MDA-MB-231 cells were treated with Chondramide (1 or 24 h), stimulated with EGF (5 min) and analyzed via Western blot analysis on EGFR, Akt and Erk. Left panel: one representative Western blot is shown. Right: Densitometric analysis of Western blots. *, p<0.05 One-way ANOVA, Tukey post-test, n = 3.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0112542.g005