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An Elevated Peripheral Blood Lymphocyte-to-Monocyte Ratio Predicts Favorable Response and Prognosis in Locally Advanced Breast Cancer following Neoadjuvant Chemotherapy

Figure 1

Elevated LMR indicates a favorable disease-free survival (DFS) in locally advanced breast cancer patients.

A. ROC curves assessing the cut-off of LMR for predicting the occurrence of disease events in the cohort study. B. Cumulative DFS curves of locally advanced breast cancer patients with high or low LMR (number of patients, 542, number of events, 186). C. Cumulative DFS curves of locally advanced breast cancer patients with high or low ALC (number of patients, 542, number of events, 186). D. Cumulative DFS curves of locally advanced breast cancer patients with high or low AMC (number of patients, 542, number of events, 186). LMR, lymphocyte-to-monocyte ratio; ALC, absolute lymphocyte count; AMC, absolute monocyte count; DFS, disease-free survival; ROC, receiver operating characteristic; AUC, area under the curve.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0111886.g001