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Long-Distance Retinoid Signaling in the Zebra Finch Brain

Figure 15

CYP26B1 and zRalDH exhibit graded expression in higher auditory areas of adult zebra finch.

The drawing in the top left indicates approximate regions shown in A–E; the drawings on the left depict brain areas shown on the right. The middle and right columns show sections processed for ISH for CYP26B1 and zRalDH. For all images, anterior is to the right and dorsal is up; medial to lateral is represented from top to bottom. CYP26B1 is expressed in a dorsoventral gradient-like pattern throughout the caudal, caudo-medial and caudo-lateral mesopallium (CM, CMM and CLM; arrows in middle panels point to region of high expression). This distribution does not overlap with zRalDH mRNA expression, which is absent in the mesopallium; some cells in the rostral part of the caudal nidopallium express zRalDH (arrows in right panels), tapering off caudally. For other abbreviations, see table 1. Scale bar = 0.5 mm.

Figure 15

doi: https://doi.org/10.1371/journal.pone.0111722.g015