Impact of miR-21, miR-126 and miR-221 as Prognostic Factors of Clear Cell Renal Cell Carcinoma with Tumor Thrombus of the Inferior Vena Cava
Figure 5
Kaplan Meier survival analysis and receiver operating characteristics (ROC) curve for CSS in ccRCC/TT patients (n = 37) stratified by the CRS for miR-21, miR-126 and miR-221.
CRS were calculated as described in the material and methods part. A) ROC curve; the cross indicates the calculated cutoff score for the CRS resulting in the highest sensitivity and specificity The selected cut off score is indicated in graph B) The ccRCC/TT study cohort (n = 37) was stratified by the calculated risk score using Kaplan Meier analysis. Kaplan Meier curves with log rank test and risk stratification by CRS are shown. C) Uni- and multivariate Cox regression analysis for cancer related death in the ccRCC/TT collective determined by relative goodness of fit with AIC including selected miRs and clinico-pathological factors as variable.