Changes in Metabolic Profiles during Acute Kidney Injury and Recovery following Ischemia/Reperfusion
Figure 9
The change of metabolites involved in osmotic regulation.
C57BL/6 mice were subjected to sham operation or 25 minutes of bilateral renal ischemia with 2 hours, 48 hours, and 1 week of reperfusion. The renal cortex, renal medulla and plasma samples were collected at sacrifice for metabolites profiling. The red colored numbers indicate statistically significant increase (P≤0.05). The green colored numbers indicate statistically significant decrease (P≤0.05). The blue colored numbers indicate narrowly missed statistical cutoff for significance (0.05<P<0.1). (A) The glucose derived polyols; (B) other polyols.