Toxic Effects of Maternal Zearalenone Exposure on Intestinal Oxidative Stress, Barrier Function, Immunological and Morphological Changes in Rats
Figure 2
Effects of zearalenone (ZEN) on the expression of immune genes in the jejunum of rats.
(A) Interleukin (IL)-1α; (B) IL-1β; (C) IL-6; (D) IL-8; (E) Tumor necrosis factor (TNF)-α. The relative gene expression for each gene was calculated relative to the gene expression of the ZEN0 group. β-actin was chosen as a reference gene having the same relative expression mean in the ZEN0 group as in the treated groups. ZEN 0, ZEN 50, ZEN 100, and ZEN 150 means a daily feeding with ZEN at doses of 0.3, 48.5, 97.6, and 146.0 mg/kg respectively, at gestation days 1 to 7. All of the values are expressed as the means ±SEM (n = 12). a, b, c means within a row with no common superscripts differ significantly (P<0.05).