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Establishment of a 10-Plex Quantitative Fluorescent-PCR Assay for Rapid Diagnosis of Sex Chromosome Aneuploidies

Figure 3

Comparison of peak ratios of AMXY to autosomal internal controls ((A) D21S11 and (B) D13S305) between confirmed Tuner samples and normal samples. Unpaired t tests were used.

***P<0.0001. Dash lines showed the cutoff values of AMXY/D21S11 (0.55) and AMXY/D13S305 (0.5), which would be used as the criteria for determination of Turner syndromes when suspected cases show single peaks for all X-linked markers and no peaks for AMY and SRY.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0106307.g003