Inhibition of c-Abl Kinase Activity Renders Cancer Cells Highly Sensitive to Mitoxantrone
Figure 2
Combination of MX and imatinib activates caspase cascades.
HeLa cells were treated with indicated drugs for 48 h. Then, fresh medium was replaced and caspase 3/7 activity was measured using ELISA assay. Experiment was done in triplicate, mean ± SD. *** p<0.001 T-test.