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Oxygen-Carbon Nanotubes as a Chemotherapy Sensitizer for Paclitaxel in Breast Cancer Treatment

Figure 4

Effect of oxygen-CNTs and paclitaxel on survivin, Ki67 and HIF-1α mRNA expression.

A. Oxygen-CNTs and affect survivin and Ki67 mRNA expression under hypoxic conditions. Typical figure (left) and analysis (right). 1: hypoxia group; 2: paclitaxel group; 3: oxygen-CNTs group. B. Effect of oxygen-CNTs on HIF-1α mRNA expression under normal and hypoxic conditions. Typical figure (left) and analysis (right). 1: normoxia group; 2: hypoxia group; 3: paclitaxel group; 4: oxygen-CNTs group.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0104209.g004