MDSCs Mediate Angiogenesis and Predispose Canine Mammary Tumor Cells for Metastasis via IL-28/IL-28RA (IFN-λ) Signaling
Figure 2
Vessel formation (3D) by HUVECs.
Representative pictures showing 3D vessel formation by HUVECs due to co-culture with P114 canine mammary control cells (mock-transfected), cells treated with Il-28ra-specific siRNA, cells treated with IL-28 (before the experiment), cells treated with IL-28 during the experiment and positive and negative control cells, as well as only IL-28 treatment.