Mutations of C-Reactive Protein (CRP) -286 SNP, APC and p53 in Colorectal Cancer: Implication for a CRP-Wnt Crosstalk
Figure 3
The distribution of somatic mutations of CRP-286 SNP and APC in tumors.
The CRP-286 SNP mutations tend to co-occur with APC mutations in colon (A) (Fisher’s exact test, two-tailed, p = 0.47) and rectal cancers (B) (Fisher’s exact test, two-tailed, p = 0.04). Each rectangle represents one tumor sample with grey color denotes wild type status. The bar graphs on the right indicate the percentages of patients carrying APC mutations in two patient groups with or without CRP-286 mutations.